Ecological Consistency of SSU rRNA-Based Operational Taxonomic Units at a Global Scale

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Ecological Consistency of SSU rRNA-Based Operational Taxonomic Units at a Global Scale

Operational Taxonomic Units (OTUs), usually defined as clusters of similar 16S/18S rRNA sequences, are the most widely used basic diversity units in large-scale characterizations of microbial communities. However, it remains unclear how well the various proposed OTU clustering algorithms approximate 'true' microbial taxa. Here, we explore the ecological consistency of OTUs--based on the assumpt...

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ژورنال

عنوان ژورنال: PLoS Computational Biology

سال: 2014

ISSN: 1553-7358

DOI: 10.1371/journal.pcbi.1003594